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Gfi1aa/Lsd1 Facilitates Hemangioblast Differentiation Into Primitive Erythrocytes by Targeting etv2 and sox7 in Zebrafish

The first wave of hematopoiesis is the primitive hematopoiesis, which produces embryonic erythroid and myeloid cells. Primitive erythrocytes are thought to be generated from bipotent hemangioblasts, but the molecular basis remains unclear. Transcriptional repressors Gfi1aa and Gfi1b have been shown...

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Detalles Bibliográficos
Autores principales: Wu, Mei, Chen, Qi, Li, Jing, Xu, Yue, Lian, Junwei, Liu, Yongxiang, Meng, Ping, Zhang, Yiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790037/
https://www.ncbi.nlm.nih.gov/pubmed/35096818
http://dx.doi.org/10.3389/fcell.2021.786426