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Oridonin Alleviates LPS-Induced Depression by Inhibiting NLRP3 Inflammasome via Activation of Autophagy

Objective: Oridonin (Ori) is a diterpene compound that has multiple biological properties. Here, our study was conducted to observe the therapeutic effect of Ori on depression as well as to uncover the mechanism. Methods: Lipopolysaccharide (LPS)-induced depression models were established both in C5...

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Detalles Bibliográficos
Autores principales: Li, Chunyan, Zhu, Yuehua, Wu, Yuanyuan, Fu, Meiyuan, Wu, Yiling, Wu, Yuehong, Qiu, Yinger, Zhang, Hui, Ding, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790066/
https://www.ncbi.nlm.nih.gov/pubmed/35096901
http://dx.doi.org/10.3389/fmed.2021.813047