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Enhanced Angiogenesis by 11βHSD1 Blockage Is Insufficient to Improve Reperfusion Following Hindlimb Ischaemia

Background: Critical limb ischaemia (CLI), which is estimated to affect 2 million people in the United States, reduces quality of life, is associated with high morbidity and mortality, and has limited treatment options. Direct stimulation of angiogenesis using proangiogenic growth factors has been i...

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Detalles Bibliográficos
Autores principales: Wu, Junxi, Miller, Eileen, Davidson, Callam, Walker, Brian R., Hadoke, Patrick W. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790072/
https://www.ncbi.nlm.nih.gov/pubmed/35097015
http://dx.doi.org/10.3389/fcvm.2021.795823