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Retinal Development and Pathophysiology in Kcnj13 Knockout Mice

Purpose: We constructed and characterized knockout and conditional knockout mice for KCNJ13, encoding the inwardly rectifying K(+) channel of the Kir superfamily Kir7.1, mutations in which cause both Snowflake Vitreoretinal Degeneration (SVD) and Retinitis pigmentosa (RP) to further elucidate the pa...

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Detalles Bibliográficos
Autores principales: Jiao, Xiaodong, Ma, Zhiwei, Lei, Jingqi, Liu, Pinghu, Cai, Xiaoyu, Shahi, Pawan K., Chan, Chi-Chao, Fariss, Robert, Pattnaik, Bikash R., Dong, Lijin, Hejtmancik, J. Fielding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790323/
https://www.ncbi.nlm.nih.gov/pubmed/35096838
http://dx.doi.org/10.3389/fcell.2021.810020