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Cluster mean-field theory accurately predicts statistical properties of large-scale DNA methylation patterns

The accurate establishment and maintenance of DNA methylation patterns is vital for mammalian development and disruption to these processes causes human disease. Our understanding of DNA methylation mechanisms has been facilitated by mathematical modelling, particularly stochastic simulations. Megab...

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Detalles Bibliográficos
Autores principales: Kerr, Lyndsay, Sproul, Duncan, Grima, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790364/
https://www.ncbi.nlm.nih.gov/pubmed/35078341
http://dx.doi.org/10.1098/rsif.2021.0707