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Cluster mean-field theory accurately predicts statistical properties of large-scale DNA methylation patterns
The accurate establishment and maintenance of DNA methylation patterns is vital for mammalian development and disruption to these processes causes human disease. Our understanding of DNA methylation mechanisms has been facilitated by mathematical modelling, particularly stochastic simulations. Megab...
Autores principales: | Kerr, Lyndsay, Sproul, Duncan, Grima, Ramon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790364/ https://www.ncbi.nlm.nih.gov/pubmed/35078341 http://dx.doi.org/10.1098/rsif.2021.0707 |
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