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A high-throughput assay for directly monitoring nucleolar rRNA biogenesis

Studies of the regulation of nucleolar function are critical for ascertaining clearer insights into the basic biological underpinnings of ribosome biogenesis (RB), and for future development of therapeutics to treat cancer and ribosomopathies. A number of high-throughput primary assays based on morp...

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Detalles Bibliográficos
Autores principales: Bryant, Carson J., McCool, Mason A., Abriola, Laura, Surovtseva, Yulia V., Baserga, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790372/
https://www.ncbi.nlm.nih.gov/pubmed/35078352
http://dx.doi.org/10.1098/rsob.210305