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Statin as a therapeutic agent in gastroenterological cancer

Statins inhibit 3-hydroxy-3-methylglutaryl-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, and are widely used as an effective and safe approach handle hypercholesterolemia. The mevalonate pathway is a vital metabolic pathway that uses acetyl-CoA to generate isoprenoids and sterol...

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Detalles Bibliográficos
Autores principales: Uemura, Norio, Hayashi, Hiromitsu, Baba, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790423/
https://www.ncbi.nlm.nih.gov/pubmed/35116106
http://dx.doi.org/10.4251/wjgo.v14.i1.110