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Statin as a therapeutic agent in gastroenterological cancer
Statins inhibit 3-hydroxy-3-methylglutaryl-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, and are widely used as an effective and safe approach handle hypercholesterolemia. The mevalonate pathway is a vital metabolic pathway that uses acetyl-CoA to generate isoprenoids and sterol...
Autores principales: | Uemura, Norio, Hayashi, Hiromitsu, Baba, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790423/ https://www.ncbi.nlm.nih.gov/pubmed/35116106 http://dx.doi.org/10.4251/wjgo.v14.i1.110 |
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