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p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse

Persistent inactivity promotes skeletal muscle atrophy, marked by mitochondrial aberrations that affect strength, mobility, and metabolic health leading to the advancement of disease. Mitochondrial quality control (MQC) pathways include biogenesis (synthesis), mitophagy/lysosomal turnover, and the m...

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Detalles Bibliográficos
Autores principales: Memme, Jonathan M., Oliveira, Ashley N., Hood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790503/
https://www.ncbi.nlm.nih.gov/pubmed/34958797
http://dx.doi.org/10.1016/j.jbc.2021.101540