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p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse
Persistent inactivity promotes skeletal muscle atrophy, marked by mitochondrial aberrations that affect strength, mobility, and metabolic health leading to the advancement of disease. Mitochondrial quality control (MQC) pathways include biogenesis (synthesis), mitophagy/lysosomal turnover, and the m...
Autores principales: | Memme, Jonathan M., Oliveira, Ashley N., Hood, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790503/ https://www.ncbi.nlm.nih.gov/pubmed/34958797 http://dx.doi.org/10.1016/j.jbc.2021.101540 |
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