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HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS

The aberrant translation of a repeat expansion in chromosome 9 open reading frame 72 (C9orf72), the most common cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), results in the accumulation of toxic dipeptide repeat (DPR) proteins in the central nervous system We have f...

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Detalles Bibliográficos
Autores principales: del Rosso, Giulia, Carlomagno, Yari, Todd, Tiffany W., Jones, Caroline Y., Prudencio, Mercedes, Daughrity, Lillian M., Yue, Mei, Jansen-West, Karen, Tong, Jimei, Shao, Wei, Wu, Yanwei, Castanedes-Casey, Monica, Tabassian, Lilia, Oskarsson, Björn, Ling, Karen, Rigo, Frank, Dickson, Dennis W., Yao, Tso-Pang, Petrucelli, Leonard, Cook, Casey N., Zhang, Yong Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790530/
https://www.ncbi.nlm.nih.gov/pubmed/35096836
http://dx.doi.org/10.3389/fcell.2021.809942