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Synthesis of broad-specificity activity-based probes for exo-β-mannosidases

Exo-β-mannosidases are a broad class of stereochemically retaining hydrolases that are essential for the breakdown of complex carbohydrate substrates found in all kingdoms of life. Yet the detection of exo-β-mannosidases in complex biological samples remains challenging, necessitating the developmen...

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Detalles Bibliográficos
Autores principales: McGregor, Nicholas G. S., Kuo, Chi-Lin, Beenakker, Thomas J. M., Wong, Chun-Sing, Offen, Wendy A., Armstrong, Zachary, Florea, Bogdan I., Codée, Jeroen D. C., Overkleeft, Herman S., Aerts, Johannes M. F. G., Davies, Gideon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790593/
https://www.ncbi.nlm.nih.gov/pubmed/35015006
http://dx.doi.org/10.1039/d1ob02287c