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Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

BACKGROUND: Sarcolipin and uncoupling protein 3 (UCP3) mediate muscle-based non-shivering thermogenesis (NST) to improve metabolic homeostasis. The impacts of maternal obesity (MO) and maternal exercise (ME) on NST in offspring muscle remain unexamined. METHODS: Female mice were fed with a control d...

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Detalles Bibliográficos
Autores principales: Son, Jun Seok, Chae, Song Ah, Zhao, Liang, Wang, Hongyang, de Avila, Jeanene M., Zhu, Mei-Jun, Jiang, Zhihua, Du, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790600/
https://www.ncbi.nlm.nih.gov/pubmed/35081489
http://dx.doi.org/10.1016/j.ebiom.2022.103842