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Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling
BACKGROUND: Sarcolipin and uncoupling protein 3 (UCP3) mediate muscle-based non-shivering thermogenesis (NST) to improve metabolic homeostasis. The impacts of maternal obesity (MO) and maternal exercise (ME) on NST in offspring muscle remain unexamined. METHODS: Female mice were fed with a control d...
Autores principales: | Son, Jun Seok, Chae, Song Ah, Zhao, Liang, Wang, Hongyang, de Avila, Jeanene M., Zhu, Mei-Jun, Jiang, Zhihua, Du, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790600/ https://www.ncbi.nlm.nih.gov/pubmed/35081489 http://dx.doi.org/10.1016/j.ebiom.2022.103842 |
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