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Asymmetric synthesis of isochromanone derivatives via trapping carboxylic oxonium ylides and aldol cascade

An efficient asymmetric synthesis of isochromanone derivatives was realized through Z-selective-1,3-OH insertion/aldol cyclization reaction involving acyclic carboxylic oxonium ylides. The combination of achiral dirhodium salts and chiral N,N′-dioxide–metal complexes, along with the use of α-diazoke...

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Detalles Bibliográficos
Autores principales: Lang, Jiawen, Wang, Siyuan, He, Changli, Liu, Xiaohua, Feng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790771/
https://www.ncbi.nlm.nih.gov/pubmed/35211283
http://dx.doi.org/10.1039/d1sc06025b