A comparative study of next-generation sequencing and fragment analysis for the detection and allelic ratio determination of FLT3 internal tandem duplication

BACKGROUND: Currently, FLT3 internal tandem duplication (ITD) is tested by fragment analysis. With next-generation sequencing (NGS), however, not only FLT3 ITD but also other mutations can be detected, which can provide more genetic information on disease. METHODS: We retrospectively reviewed the re...

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Detalles Bibliográficos
Autores principales: Kim, Jin Ju, Lee, Kwang Seob, Lee, Taek Gyu, Lee, Seungjae, Shin, Saeam, Lee, Seung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790841/
https://www.ncbi.nlm.nih.gov/pubmed/35081962
http://dx.doi.org/10.1186/s13000-022-01202-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790841/
https://www.ncbi.nlm.nih.gov/pubmed/35081962
http://dx.doi.org/10.1186/s13000-022-01202-x

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