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Detection and identification of cis-regulatory elements using change-point and classification algorithms

BACKGROUND: Transcriptional regulation is primarily mediated by the binding of factors to non-coding regions in DNA. Identification of these binding regions enhances understanding of tissue formation and potentially facilitates the development of gene therapies. However, successful identification of...

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Detalles Bibliográficos
Autores principales: Maderazo, Dominic, Flegg, Jennifer A., Algama, Manjula, Ramialison, Mirana, Keith, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790847/
https://www.ncbi.nlm.nih.gov/pubmed/35078412
http://dx.doi.org/10.1186/s12864-021-08190-0