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Detection and identification of cis-regulatory elements using change-point and classification algorithms
BACKGROUND: Transcriptional regulation is primarily mediated by the binding of factors to non-coding regions in DNA. Identification of these binding regions enhances understanding of tissue formation and potentially facilitates the development of gene therapies. However, successful identification of...
Autores principales: | Maderazo, Dominic, Flegg, Jennifer A., Algama, Manjula, Ramialison, Mirana, Keith, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790847/ https://www.ncbi.nlm.nih.gov/pubmed/35078412 http://dx.doi.org/10.1186/s12864-021-08190-0 |
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