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Human embryonic mesenchymal lung-conditioned medium promotes differentiation to myofibroblast and loss of stemness phenotype in lung adenocarcinoma cell lines

BACKGROUND: When genes responsible for normal embryonic development are abnormally expressed in adults, it can lead to tumor development. This can suggest that the same mechanism that controls embryonic differentiation can also control tumor differentiation. We hypothesize that the malignant phenoty...

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Detalles Bibliográficos
Autores principales: Canals, Jordi, Navarro, Alfons, Vila, Cristina, Canals, Josep M., Díaz, Tania, Acosta-Plasencia, Melissa, Cros-Font, Coralí, Han, Bing, He, Yangyi, Monzó, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790861/
https://www.ncbi.nlm.nih.gov/pubmed/35081981
http://dx.doi.org/10.1186/s13046-021-02206-z