A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression

BACKGROUND: Tyrosine kinase inhibitors (TKIs) alone and in combination with immune checkpoint inhibitors (ICIs) have been shown to be beneficial for the survival of metastatic renal cell carcinoma (mRCC) patients, but resistance to targeted therapy and ICIs is common in the clinic. Understanding the...

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Detalles Bibliográficos
Autores principales: Liu, Wentao, Ren, Dianyun, Xiong, Wei, Jin, Xin, Zhu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790872/
https://www.ncbi.nlm.nih.gov/pubmed/35081978
http://dx.doi.org/10.1186/s13046-022-02253-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8790872/
https://www.ncbi.nlm.nih.gov/pubmed/35081978
http://dx.doi.org/10.1186/s13046-022-02253-0

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