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Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells

A large body of evidence suggests the involvement of the ATP-gated purinergic receptor P2X7 (P2X7R) in neurodegenerative diseases, including Alzheimer’s disease. While it is well-described to be present and functional on microglia cells contributing to inflammatory responses, some reports suggest a...

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Detalles Bibliográficos
Autores principales: Francistiová, Linda, Vörös, Kinga, Lovász, Zsófia, Dinnyés, András, Kobolák, Julianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791009/
https://www.ncbi.nlm.nih.gov/pubmed/35095416
http://dx.doi.org/10.3389/fnmol.2021.793769