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Methods for Studying Site-Specific O-GlcNAc Modifications: Successes, Limitations, and Important Future Goals

[Image: see text] O-GlcNAcylation is a dynamic post-translational modification which affects myriad proteins, cellular functions, and disease states. Its presence or absence modulates protein function via differential protein- and site-specific mechanisms, necessitating innovative techniques to prob...

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Detalles Bibliográficos
Autores principales: Moon, Stuart P., Javed, Afraah, Hard, Eldon R., Pratt, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791055/
https://www.ncbi.nlm.nih.gov/pubmed/35098223
http://dx.doi.org/10.1021/jacsau.1c00455