Intralymphatic GAD-alum Injection Modulates B Cell Response and Induces Follicular Helper T Cells and PD-1+ CD8+ T Cells in Patients With Recent-Onset Type 1 Diabetes

Antigen-specific immunotherapy is an appealing strategy to preserve beta-cell function in type 1 diabetes, although the approach has yet to meet its therapeutic endpoint. Direct administration of autoantigen into lymph nodes has emerged as an alternative administration route that can improve the eff...

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Detalles Bibliográficos
Autores principales: Barcenilla, Hugo, Pihl, Mikael, Wahlberg, Jeanette, Ludvigsson, Johnny, Casas, Rosaura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791064/
https://www.ncbi.nlm.nih.gov/pubmed/35095874
http://dx.doi.org/10.3389/fimmu.2021.797172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791064/
https://www.ncbi.nlm.nih.gov/pubmed/35095874
http://dx.doi.org/10.3389/fimmu.2021.797172

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