Deglycosylated EpCAM regulates proliferation by enhancing autophagy of breast cancer cells via PI3K/Akt/mTOR pathway

Autophagy is an important regulator of cellular homeostasis and its dysregulation often results in cancer. Aberrant glycosylation induced by oncogenic transformation contributes to tumor invasion and metastasis. In a previous study, we have demonstrated that EpCAM, a glycosylation protein, is associ...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Wang, Qijun, Zhao, Qian, Yang, Fan, Liu, Tingjiao, Huang, Xiaohua, Yan, Qiu, Yang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791205/
https://www.ncbi.nlm.nih.gov/pubmed/34983878
http://dx.doi.org/10.18632/aging.203795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791205/
https://www.ncbi.nlm.nih.gov/pubmed/34983878
http://dx.doi.org/10.18632/aging.203795

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