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TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer

5-Fluorouracil (5-Fu) is the first-line chemotherapeutic option for colorectal cancer. However, its efficacy is inhibited by drug resistance. Cytokines play an important role in tumor drug resistance, even though their mechanisms are largely unknown. Using a cytokine array, we established that tissu...

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Detalles Bibliográficos
Autores principales: Zhang, Guolin, Luo, Xin, Wang, Zian, Xu, Jianbin, Zhang, Wei, Chen, Engeng, Meng, Qing, Wang, Di, Huang, Xuefeng, Zhou, Wei, Song, Zhangfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791226/
https://www.ncbi.nlm.nih.gov/pubmed/35022331
http://dx.doi.org/10.18632/aging.203793