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TIMP-2 regulates 5-Fu resistance via the ERK/MAPK signaling pathway in colorectal cancer
5-Fluorouracil (5-Fu) is the first-line chemotherapeutic option for colorectal cancer. However, its efficacy is inhibited by drug resistance. Cytokines play an important role in tumor drug resistance, even though their mechanisms are largely unknown. Using a cytokine array, we established that tissu...
Autores principales: | Zhang, Guolin, Luo, Xin, Wang, Zian, Xu, Jianbin, Zhang, Wei, Chen, Engeng, Meng, Qing, Wang, Di, Huang, Xuefeng, Zhou, Wei, Song, Zhangfa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791226/ https://www.ncbi.nlm.nih.gov/pubmed/35022331 http://dx.doi.org/10.18632/aging.203793 |
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