Next-Generation Sequencing Reveals a Very Low Prevalence of Deleterious Mutations of Homologous Recombination Repair Genes and Homologous Recombination Deficiency in Ovarian Clear Cell Carcinoma

Ovarian clear cell carcinoma (OCCC) is aggressive and drug-resistant. The prevalence of homologous recombination repair (HRR) gene mutations and homologous recombination deficiency (HRD) remains largely unknown. It is also not clear whether the commonly used molecular-based classification for endome...

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Detalles Bibliográficos
Autores principales: Liu, Hangqi, Zhang, Zhiwen, Chen, Longyun, Pang, Junyi, Wu, Huanwen, Liang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791260/
https://www.ncbi.nlm.nih.gov/pubmed/35096598
http://dx.doi.org/10.3389/fonc.2021.798173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791260/
https://www.ncbi.nlm.nih.gov/pubmed/35096598
http://dx.doi.org/10.3389/fonc.2021.798173

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