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Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
Most mitochondrial proteins are translated in the cytosol and imported into mitochondria. Mutations in the mitochondrial protein import machinery cause human pathologies. However, a lack of suitable tools to measure protein uptake across the mitochondrial proteome has prevented the identification of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791276/ https://www.ncbi.nlm.nih.gov/pubmed/34847359 http://dx.doi.org/10.1016/j.molcel.2021.11.004 |