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Hybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments

The ability of RNAs to form specific contacts with other macromolecules provides an important mechanism for subcellular compartmentalization. Here we describe a suite of hybridization-proximity (HyPro) labeling technologies for unbiased discovery of proteins (HyPro-MS) and transcripts (HyPro-seq) as...

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Detalles Bibliográficos
Autores principales: Yap, Karen, Chung, Tek Hong, Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791277/
https://www.ncbi.nlm.nih.gov/pubmed/34741808
http://dx.doi.org/10.1016/j.molcel.2021.10.009