A Structurally Conserved RNA Element within SARS-CoV-2 ORF1a RNA and S mRNA Regulates Translation in Response to Viral S Protein-Induced Signaling in Human Lung Cells

The positive-sense, single-stranded RNA genome SARS-CoV-2 harbors functionally important cis-acting elements governing critical aspects of viral gene expression. However, insights on how these elements sense various signals from the host cell and regulate viral protein synthesis are lacking. Here, w...

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Detalles Bibliográficos
Autores principales: Basu, Abhijit, Penumutchu, Srinivasa, Nguyen, Kien, Mbonye, Uri, Tolbert, Blanton S., Karn, Jonathan, Komar, Anton A., Mazumder, Barsanjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791291/
https://www.ncbi.nlm.nih.gov/pubmed/34757848
http://dx.doi.org/10.1128/JVI.01678-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791291/
https://www.ncbi.nlm.nih.gov/pubmed/34757848
http://dx.doi.org/10.1128/JVI.01678-21

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