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Platelet Membrane-Coated Nanocarriers Targeting Plaques to Deliver Anti-CD47 Antibody for Atherosclerotic Therapy

Atherosclerosis, the principle cause of cardiovascular disease (CVD) worldwide, is mainly characterized by the pathological accumulation of diseased vascular cells and apoptotic cellular debris. Atherogenesis is associated with the upregulation of CD47, a key antiphagocytic molecule that is known to...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Zhou, Zhongyi, Hu, Cheng, Maitz, Manfred F., Yang, Li, Luo, Rifang, Wang, Yunbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791388/
https://www.ncbi.nlm.nih.gov/pubmed/35118420
http://dx.doi.org/10.34133/2022/9845459