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KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas

Endometrioid endometrial carcinomas (EECs) are the most common histological subtype of uterine cancer. Late-stage disease is an adverse prognosticator for EEC. The purpose of this study was to analyze EEC exome mutation data to identify late-stage-specific statistically significantly mutated genes (...

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Detalles Bibliográficos
Autores principales: Rudd, Meghan L., Hansen, Nancy F., Zhang, Xiaolu, Urick, Mary Ellen, Zhang, Suiyuan, Merino, Maria J., Mullikin, James C., Brody, Lawrence C., Bell, Daphne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791453/
https://www.ncbi.nlm.nih.gov/pubmed/35081118
http://dx.doi.org/10.1371/journal.pone.0251286