Anti–IL-6 cytokine treatment has no impact on elevated hematocrit or splenomegaly in a polycythemia vera mouse model

Somatic mutations in JAK2, MPL and Calreticulin and inflammation play a key role in pathophysiology of chronic myeloproliferative neoplasia (CMN). One of the most prominent cytokines elevated in serum of Polycythemia vera patients is interleukin-6 (IL-6). Currently, it is being discussed whether sup...

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Detalles Bibliográficos
Autores principales: Baldauf, Conny K., Müller, Peter, Haage, Tobias R., Adam-Frey, Stephanie, Lokau, Juliane, Garbers, Christoph, Fischer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791576/
https://www.ncbi.nlm.nih.gov/pubmed/34559181
http://dx.doi.org/10.1182/bloodadvances.2021004379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791576/
https://www.ncbi.nlm.nih.gov/pubmed/34559181
http://dx.doi.org/10.1182/bloodadvances.2021004379

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