VpreB surrogate light chain expression in B-lineage ALL: a report from the Children’s Oncology Group

Immunotherapies directed against B-cell surface markers have been a common developmental strategy to treat B-cell malignancies. The immunoglobulin heavy chain surrogate light chain (SLC), comprising the VpreB1 (CD179a) and Lamda5 (CD179b) subunits, is expressed on pro- and pre-B cells, where it gove...

Descripción completa

Detalles Bibliográficos
Autores principales: Winter, Stuart S., McCaustland, Amanda, Qu, Chunxu, Simeona, No’eau, Heerema, Nyla A., Carroll, Andrew J., Wood, Brent L., Gheorghe, Gabriela, Mullighan, Charles G., Wilson, Bridget S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791581/
https://www.ncbi.nlm.nih.gov/pubmed/34662891
http://dx.doi.org/10.1182/bloodadvances.2021005245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791581/
https://www.ncbi.nlm.nih.gov/pubmed/34662891
http://dx.doi.org/10.1182/bloodadvances.2021005245

Ejemplares similares