Activation by cleavage of the epithelial Na(+) channel α and γ subunits independently coevolved with the vertebrate terrestrial migration

Vertebrates evolved mechanisms for sodium conservation and gas exchange in conjunction with migration from aquatic to terrestrial habitats. Epithelial Na(+) channel (ENaC) function is critical to systems responsible for extracellular fluid homeostasis and gas exchange. ENaC is activated by cleavage...

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Detalles Bibliográficos
Autores principales: Wang, Xue-Ping, Balchak, Deidra M, Gentilcore, Clayton, Clark, Nathan L, Kashlan, Ossama B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791634/
https://www.ncbi.nlm.nih.gov/pubmed/34984981
http://dx.doi.org/10.7554/eLife.75796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791634/
https://www.ncbi.nlm.nih.gov/pubmed/34984981
http://dx.doi.org/10.7554/eLife.75796

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