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Activation by cleavage of the epithelial Na(+) channel α and γ subunits independently coevolved with the vertebrate terrestrial migration
Vertebrates evolved mechanisms for sodium conservation and gas exchange in conjunction with migration from aquatic to terrestrial habitats. Epithelial Na(+) channel (ENaC) function is critical to systems responsible for extracellular fluid homeostasis and gas exchange. ENaC is activated by cleavage...
Autores principales: | Wang, Xue-Ping, Balchak, Deidra M, Gentilcore, Clayton, Clark, Nathan L, Kashlan, Ossama B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791634/ https://www.ncbi.nlm.nih.gov/pubmed/34984981 http://dx.doi.org/10.7554/eLife.75796 |
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