Cargando…

Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae

Rap1 is the main protein that binds double-stranded telomeric DNA in Saccharomyces cerevisiae. Examination of the telomere functions of Rap1 is complicated by the fact that it also acts as a transcriptional regulator of hundreds of genes and is encoded by an essential gene. In this study, we disrupt...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosas Bringas, Fernando Rodrigo, Stinus, Sonia, de Zoeten, Pien, Cohn, Marita, Chang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791636/
https://www.ncbi.nlm.nih.gov/pubmed/35044907
http://dx.doi.org/10.7554/eLife.74090