Progranulin Suppressed Autoimmune Uveitis and Autoimmune Neuroinflammation by Inhibiting Th1/Th17 Cells and Promoting Treg Cells and M2 Macrophages

BACKGROUND AND OBJECTIVES: Progranulin (PGRN) is an important immune regulatory molecule in several immune-mediated diseases. The objective of this study is to investigate the role of PGRN in uveitis and its counterpart, experimental autoimmune uveitis (EAU), and experimental autoimmune encephalomye...

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Detalles Bibliográficos
Autores principales: Wang, Chaokui, Zhou, Wenjun, Su, Guannan, Hu, Jianping, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791655/
https://www.ncbi.nlm.nih.gov/pubmed/35082168
http://dx.doi.org/10.1212/NXI.0000000000001133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791655/
https://www.ncbi.nlm.nih.gov/pubmed/35082168
http://dx.doi.org/10.1212/NXI.0000000000001133

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