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Accelerated developmental adipogenesis programs adipose tissue dysfunction and cardiometabolic risk in offspring born to dams with metabolic dysfunction

This study determined if a perturbation in in utero adipogenesis leading to later life adipose tissue (AT) dysfunction underlies programming of cardiometabolic risk in offspring born to dams with metabolic dysfunction. Female mice heterozygous for the leptin receptor deficiency (Het(db)) had 2.4-fol...

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Detalles Bibliográficos
Autores principales: Mikolajczak, Anna, Sallam, Nada A., Singh, Radha D., Scheidl, Taylor B., Walsh, Emma J., Larion, Sebastian, Huang, Carol, Thompson, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791794/
https://www.ncbi.nlm.nih.gov/pubmed/34459218
http://dx.doi.org/10.1152/ajpendo.00229.2021