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Accelerated developmental adipogenesis programs adipose tissue dysfunction and cardiometabolic risk in offspring born to dams with metabolic dysfunction
This study determined if a perturbation in in utero adipogenesis leading to later life adipose tissue (AT) dysfunction underlies programming of cardiometabolic risk in offspring born to dams with metabolic dysfunction. Female mice heterozygous for the leptin receptor deficiency (Het(db)) had 2.4-fol...
Autores principales: | Mikolajczak, Anna, Sallam, Nada A., Singh, Radha D., Scheidl, Taylor B., Walsh, Emma J., Larion, Sebastian, Huang, Carol, Thompson, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791794/ https://www.ncbi.nlm.nih.gov/pubmed/34459218 http://dx.doi.org/10.1152/ajpendo.00229.2021 |
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