GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

The passive transport of glucose and related hexoses in human cells is facilitated by members of the glucose transporter family (GLUT, SLC2 gene family). GLUT3 is a high-affinity glucose transporter primarily responsible for glucose entry in neurons. Changes in its expression have been implicated in...

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Detalles Bibliográficos
Autores principales: Iancu, Cristina V., Bocci, Giovanni, Ishtikhar, Mohd, Khamrai, Moumita, Oreb, Mislav, Oprea, Tudor I., Choe, Jun-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791944/
https://www.ncbi.nlm.nih.gov/pubmed/35082341
http://dx.doi.org/10.1038/s41598-022-05383-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791944/
https://www.ncbi.nlm.nih.gov/pubmed/35082341
http://dx.doi.org/10.1038/s41598-022-05383-9

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