Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism

The pedunculopontine nucleus (PPN) is a locomotor command area containing glutamatergic neurons that control locomotor initiation and maintenance. These motor actions are deficient in Parkinson’s disease (PD), where dopaminergic neurodegeneration alters basal ganglia activity. Being downstream of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Masini, Débora, Kiehn, Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791953/
https://www.ncbi.nlm.nih.gov/pubmed/35082287
http://dx.doi.org/10.1038/s41467-022-28075-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791953/
https://www.ncbi.nlm.nih.gov/pubmed/35082287
http://dx.doi.org/10.1038/s41467-022-28075-4

Ejemplares similares