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Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism
The pedunculopontine nucleus (PPN) is a locomotor command area containing glutamatergic neurons that control locomotor initiation and maintenance. These motor actions are deficient in Parkinson’s disease (PD), where dopaminergic neurodegeneration alters basal ganglia activity. Being downstream of th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791953/ https://www.ncbi.nlm.nih.gov/pubmed/35082287 http://dx.doi.org/10.1038/s41467-022-28075-4 |