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Gene and metabolite expression dependence on body mass index in human myocardium

We hypothesized that body mass index (BMI) dependent changes in myocardial gene expression and energy-related metabolites underlie the biphasic association between BMI and mortality (the obesity paradox) in cardiac surgery. We performed transcriptome profiling and measured a panel of 144 metabolites...

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Detalles Bibliográficos
Autores principales: Adebayo, Adewale S., Roman, Marius, Zakkar, Mustafa, Yusoff, Syabira, Gulston, Melanie, Joel-David, Lathishia, Anthony, Bony, Lai, Florence Y., Murgia, Antonio, Eagle-Hemming, Bryony, Sheikh, Sophia, Kumar, Tracy, Aujla, Hardeep, Dott, Will, Griffin, Julian L., Murphy, Gavin J., Woźniak, Marcin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791972/
https://www.ncbi.nlm.nih.gov/pubmed/35082386
http://dx.doi.org/10.1038/s41598-022-05562-8