The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Protein disulfide isomerase (PDI), an oxidoreductase, possesses two vicinal cysteines in the -Cys-Gly-His-Cys-motif that either form a disulfide bridge (S–S) or exist in a sulfhydryl form (-SH), forming oxidized or reduced PDI, respectively. PDI has been proven to be critical for platelet aggregatio...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Wang, Xi, Lv, Xiying, Jin, Qiushuo, Shang, Hongcai, Wang, Chih-chen, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792282/
https://www.ncbi.nlm.nih.gov/pubmed/35077997
http://dx.doi.org/10.1016/j.redox.2022.102244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792282/
https://www.ncbi.nlm.nih.gov/pubmed/35077997
http://dx.doi.org/10.1016/j.redox.2022.102244

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