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Physicochemical and Biological Evaluation of Curdlan-Poly(Lactic-Co-Glycolic Acid) Nanoparticles as a Host-Directed Therapy Against Mycobacterium Tuberculosis

Nanoparticles (NPs) that can activate macrophages infected with the tuberculosis causative pathogen Mycobacterium tuberculosis, could be an effective host directed therapy for the disease. In this study, curdlan was conjugated to poly(lactic-co-glycolic acid) (PLGA) to produce immunotherapeutic NPs....

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Detalles Bibliográficos
Autores principales: D’Souza, S, Du Plessis, SM, Egieyeh, S, Bekale, RB, Maphasa, RE, Irabin, AF, Sampson, SL, Dube, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792347/
https://www.ncbi.nlm.nih.gov/pubmed/34534573
http://dx.doi.org/10.1016/j.xphs.2021.09.012