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Inducers of the NF-κB pathways impair hepatitis delta virus replication and strongly decrease progeny infectivity in vitro

BACKGROUND & AIMS: HDV superinfection of chronically HBV-infected patients is the most aggressive form of chronic viral hepatitis, with an accelerated progression towards fibrosis/cirrhosis and increased risk of liver failure, hepatocellular carcinoma, and death. While HDV infection is not susce...

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Detalles Bibliográficos
Autores principales: Michelet, Maud, Alfaiate, Dulce, Chardès, Brieux, Pons, Caroline, Faure-Dupuy, Suzanne, Engleitner, Thomas, Farhat, Rayan, Riedl, Tobias, Legrand, Anne-Flore, Rad, Roland, Rivoire, Michel, Zoulim, Fabien, Heikenwälder, Mathias, Salvetti, Anna, Durantel, David, Lucifora, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792426/
https://www.ncbi.nlm.nih.gov/pubmed/35141510
http://dx.doi.org/10.1016/j.jhepr.2021.100415