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MED10 Drives the Oncogenicity and Refractory Phenotype of Bladder Urothelial Carcinoma Through the Upregulation of hsa-miR-590

BACKGROUND: Dysfunctional transcription machinery with associated dysregulated transcription characterizes many malignancies. Components of the mediator complex, a principal modulator of transcription, are increasingly implicated in cancer. The mediator complex subunit 10 (MED10), a vital kinase mod...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Chang, Wang, Yuan-Hung, Hu, Su-Wei, Wu, Wen-Ling, Yeh, Chi-Tai, Bamodu, Oluwaseun Adebayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8792749/
https://www.ncbi.nlm.nih.gov/pubmed/35096564
http://dx.doi.org/10.3389/fonc.2021.744937