Focal adhesion kinase-related non-kinase ameliorates liver fibrosis by inhibiting aerobic glycolysis via the FAK/Ras/c-myc/ENO1 pathway

BACKGROUND: Hepatic stellate cell (HSC) hyperactivation is a central link in liver fibrosis development. HSCs perform aerobic glycolysis to provide energy for their activation. Focal adhesion kinase (FAK) promotes aerobic glycolysis in cancer cells or fibroblasts, while FAK-related non-kinase (FRNK)...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Li, Yuan-Qing-Xiao, Zhou, Ming-Yu, Hu, Rui-Han, Zou, Gao-Liang, Li, Jian-Chao, Feng, Shu, Liu, Yong-Mei, Xin, Chang-Qin, Zhao, Xue-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793014/
https://www.ncbi.nlm.nih.gov/pubmed/35125823
http://dx.doi.org/10.3748/wjg.v28.i1.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8793014/
https://www.ncbi.nlm.nih.gov/pubmed/35125823
http://dx.doi.org/10.3748/wjg.v28.i1.123

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